Use of glycated hemoglobin and microalbuminuria in the monitoring of diabetes mellitus.
نویسندگان
چکیده
Clinical testing to assess levels of disease control and progression among persons with type 1 and type 2 diabetes mellitus is widely recommended to clinicians to improve patients’ clinical outcomes. Two important foci of recommendations for the followup care of individuals with diabetes include monitoring of glycemic status by measurement of glycated hemoglobin (GHb) and screening for kidney disease with urine albumin to assess overall disease progression and to detect potential progression toward end-organ damage. According to the American Diabetes Association’s Clinical Practice Recommendations, monitoring of glycemic status is considered a cornerstone of diabetes care and affects how physicians and patients adjust medical therapy as well as behavioral therapy (e.g., diet and exercise). Screening for urine albumin among persons with diabetes is also widely recommended for the detection and treatment of incipient diabetic nephropathy and affects the physician’s implementation of therapy to slow progression of kidney disease. Despite widespread recommendations for screening of persons with diabetes for both glycemic control and urine albumin, there has not been a systematic assembly of the literature to assess the risk relation between tests assessing longterm glycemic control or tests assessing the presence of microalbuminuria with cardiovascular, peripheral vascular, renal, and neurological outcomes (all of which represent end-organ effects of long-term diabetes). The report from which this summary was developed was commissioned by the American Association of Clinical Chemistry; it systematically reviews the literature identifying the risk relation between testing for glycemic control or urine albumin and these important clinical outcomes.
منابع مشابه
Profiling Glycated Hemoglobin Level, Lactate Dehydrogenase and Alkaline Phosphatase Activity in Gestational Diabetes Mellitus Obese Women and Compare Them with Each Other
Background and Aims: The aim of this study was profiling glycated hemoglobin (HbA1c) level, lactate dehydrogenase (LDH) and alkaline phosphatase (ALP) activity in obese women with gestational diabetes mellitus (GDM) and evaluating the correlation between them. Materials and Methods: Sample size was 90 subjects admitted to the clinical laboratory, who were divided into three groups, in each g...
متن کاملSerum biomarkers for assessing glycemic control in diabetes mellitus
Clinical evidence has revealed the association between complications Diabetes Mellitus (DM) and serum glycemic control. Thus, evaluation of the glycemic control status is crucial in the management of DM. Hemoglobin A1c (HbA1c) is the most common method for monitoring serum glycemic control. However, several confounding factors including red blood cell lifespan and hemoglobinopathies can affect ...
متن کاملGlycated Hemoglobin, Gastric Juice Nitric Oxide and Oxidative Stress in Diabetic Patients Infected by Helicobacter Pylori
Abstract Background and Objective: Recently, diabetes mellitus has been known as one of the main cause of upper gastrointestinal symptoms. Since a high prevalence of H. Pylori in diabetic patients has been reported, we aimed to evaluate the level of gastric juice Nitric Oxide (NO°), Oxidative Stress and Glycated Hemoglobin. Material and Methods: In case group, the participants were 60 diabe...
متن کاملComparative Study of Microalbuminuria and Glycated Hemoglobin Levels in Type 2 Diabetic Complications
Objective: Microalbuminuria occurs when the kidney leaks a small amount of albumin into the urine or when there is an abnormally high permeability for albumin in the renal glomerulus. Microalbuminuria is a powerful risk factor of cardiovascular disease and for the presence and severity of diabetic retinopathy and neuropathy. The aim of this study is to compare the levels of microalbumin and gly...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- Evidence report/technology assessment
دوره 84 شماره
صفحات -
تاریخ انتشار 2003